Cardiotoxicity Following Cancer Treatment
نویسندگان
چکیده
More than half of those born after 1960 will develop cancer during their lifetime. Fortunately, owing to improved diagnosis and treatment, cure rates have risen steadily over the last three decades. With an increased survivorship, more will experience adverse effects of cancer therapeutics on the heart. As the oncologist's focus begins to encompass the issues of cancer survivorship, awareness of the management of cardiac toxicity would be prudent for all physicians looking after patients with cancer.
منابع مشابه
The Effect of N-Acetylcysteine Administration to Prevent Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients
Introduction: Anthracyclines are one of the classes of chemotherapy drugs that are widely used to treat many types of cancers including breast cancer. Taking this class of medications has a significant relationship with cardiac dysfunction. N-acetylcysteine has antioxidant properties and may be effective in preventing cardiac dysfunctions. In this study, we investigated the effect of N-acetylc...
متن کاملThe Effect of N-Acetylcysteine Administration to Prevent Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients
Introduction: Anthracyclines are one of the classes of chemotherapy drugs that are widely used to treat many types of cancers including breast cancer. Taking this class of medications has a significant relationship with cardiac dysfunction. N-acetylcysteine has antioxidant properties and may be effective in preventing cardiac dysfunctions. In this study, we investigated the effect of N-acetylc...
متن کاملPathophysiology and preventive strategies of anthracycline-induced cardiotoxicity
Cardiotoxicity is a well-known complication following treatment with anthracyclines. However, they are still widely used in chemotherapy for breast cancer, lymphoma, leukemia, and sarcoma, among others. Patient clinical characteristics, such as age, sex, comorbidities, anthracycline dose and infusion schedule, and the combined anti-cancer agents used, are diverse among cancer types. It is diffi...
متن کاملEffects of 12 Weeks of Aerobic Exercise (High-Intensity Interval Training or Moderate Intensity Continuous Training) with and without Blood Flow Restriction on Anthropometric Indices in Women with Cardiotoxicity after Breast Cancer Treatment
Introduction: Cardiotoxicity is an unavoidable complication after chemotherapy. The present study investigated the effect of 12 weeks of aerobic exercise (high-intensity interval training or moderate-intensity continuous training) with and without blood flow restriction on some anthropometric indices in women with breast cancer who had chemotherapy-induced cardiotoxicity. Methods: Twenty breas...
متن کاملA journey in anthracycline-induced cardiotoxicity with emphasizing on doxorubicin: a review article
Cancer is the second leading cause of death in the United States and has become a health problem worldwide. The reported incidence of new cancer cases is estimated at 19.3 million, with a mortality rate of 10 million in the world in 2020. There are several therapeutic approaches for cancer, including chemotherapy. Chemotherapy is consuming anti-neoplastic drugs, alone or in combination. However...
متن کاملExpert opinion on the use of anthracyclines in patients with advanced breast cancer at cardiac risk.
Anthracyclines are considered to be among the most active agents for the treatment of breast cancer. However, their use is limited by cumulative, dose-related cardiotoxicity. Such cardiotoxicity results in a permanent loss of cardiac myocytes and a progressive reduction in cardiac function following each subsequent dose of anthracycline. Initially, damage to the heart is subclinical; however, i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 86 شماره
صفحات -
تاریخ انتشار 2017